Kallikrein 7/KLK7 Protein, Human, Recombinant (aa 23-252, His)

Produktübersicht

• Artikelname: Kallikrein 7/KLK7 Protein, Human, Recombinant (aa 23-252, His)
• Artikelnummer: TGM-TMPJ-00544
• Hersteller Artikelnummer: TMPJ-00544
• Alternativnummer: TGM-TMPJ-00544-1MG, TGM-TMPJ-00544-5UG, TGM-TMPJ-00544-10UG, TGM-TMPJ-00544-20UG, TGM-TMPJ-00544-50UG, TGM-TMPJ-00544-100UG, TGM-TMPJ-00544-200UG, TGM-TMPJ-00544-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: PRSS6 , Serine Protease 6 , hK7 , Stratum Corneum Chymotryptic Enzyme , hSCCE , SCCE , KLK7 , Kallikrein-7

Produktbeschreibung

Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is to regulate the desquamation process (the shedding of corneocytes from the outer layer of the epidermis) through proteolysis of the intercellular adhesive structures between corneocytes. Dysregulation of Kallikrein 7 has been linked to several inflammatory skin diseases including atopic dermatitis, psoriasis, and Netherton syndrome. Studies have shown that Kallikrein 5 is a potential physiological activator for Kallikrein 7. The proform of Kallikrein 7 can be activated by thermolysin.