CX3CL1/Fractalkine Protein, Mouse, Recombinant (His)

Produktübersicht

• Artikelname: CX3CL1/Fractalkine Protein, Mouse, Recombinant (His)
• Artikelnummer: TGM-TMPJ-00673
• Hersteller Artikelnummer: TMPJ-00673
• Alternativnummer: TGM-TMPJ-00673-1MG,TGM-TMPJ-00673-5UG,TGM-TMPJ-00673-10UG,TGM-TMPJ-00673-20UG,TGM-TMPJ-00673-50UG,TGM-TMPJ-00673-100UG,TGM-TMPJ-00673-200UG,TGM-TMPJ-00673-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: CXC3 , Cx3c , NTN , Fkn , C3Xkine , C-X3-C motif chemokine 1 , Fractalkine , ABCD-3 , Neurotactin , NTT , SCYD1 , Small-inducible cytokine D1 , CXC3C , CX3C membrane-anchored chemokine

Produktbeschreibung

Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. It consists of an extracellular NH2-terminal domain, a mucin-like stalk, a transmembrane alpha helix, and a short cytoplasmic tail. CX3CL1 exists in two forms: as a membrane-anchored or as a shed 80-95K glycoprotein. Soluble CX3CL1 is generated by limited proteolysis on the cell surface, and a disintegrin and metallopeptidase 10 (ADAM10) and ADAM17/tumor necrosis factor-alpha-converting enzyme (ADAM17/TACE) participate in this shedding. It has been suggested that ADAM10 acts in the constitutive shedding, and ADAM17 acts in response to cell activation. The protein may play a role in regulating leukocyte adhesion and migration processes at the endothelium.

Produkteigenschaften

• Reinheit: 95.00%

Bilder

TMPJ-00673