ITGA5 Protein, Human, Recombinant (His)

Produktübersicht

• Artikelname: ITGA5 Protein, Human, Recombinant (His)
• Artikelnummer: TGM-TMPJ-00810
• Hersteller Artikelnummer: TMPJ-00810
• Alternativnummer: TGM-TMPJ-00810-1MG,TGM-TMPJ-00810-5UG,TGM-TMPJ-00810-10UG,TGM-TMPJ-00810-20UG,TGM-TMPJ-00810-50UG,TGM-TMPJ-00810-100UG,TGM-TMPJ-00810-200UG,TGM-TMPJ-00810-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: FNRA , Integrin alpha-5 , Integrin Alpha-F , Fibronectin Receptor Subunit alpha , Integrin Alpha-5 , CD49 Antigen-Like Family Member E , VLA-5 , Integrin alpha-F , CD49e , ITGA5 , Fibronectin Receptor Subunit Alpha

Produktbeschreibung

Integrin alpha-5 belongs to the Integrin alpha chain family and contains 7 FG-GAP repeats. Integrin alpha-5 joins with Integrin-beta1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposis sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin alpha-5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains. In addition to adhesion, ITGA5 participates in cell-surface mediated signalling.

Produkteigenschaften

• Reinheit: 90.00%

Bilder

TMPJ-00810