CDKN1B Protein, Human, Recombinant (His)

Produktübersicht

• Artikelname: CDKN1B Protein, Human, Recombinant (His)
• Artikelnummer: TGM-TMPJ-00972
• Hersteller Artikelnummer: TMPJ-00972
• Alternativnummer: TGM-TMPJ-00972-1MG,TGM-TMPJ-00972-5UG,TGM-TMPJ-00972-10UG,TGM-TMPJ-00972-20UG,TGM-TMPJ-00972-50UG,TGM-TMPJ-00972-100UG,TGM-TMPJ-00972-200UG,TGM-TMPJ-00972-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: KIP1 , CDKN1B , Cyclin-Dependent Kinase Inhibitor p27 , Cyclin-Dependent Kinase Inhibitor 1B , p27Kip1

Produktbeschreibung

Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skeletal muscle. CDKN1B is a potent inhibitor of Cyclin E- and Cyclin A-CDK2 complexes. CDKN1B forms a complex with Cyclin Type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. In addition, CDKN1B acts as an inhibitor or an activator of Cyclin Type D-CDK4 complexes depending on its phosphorylation state and stoichometry.

Bilder

TMPJ-00972