Ubiquitin-conjugating enzyme E2(17)KB 1 , UB , UbcH5 , UBC5A , Stimulator of Fe transport , Ubiquitin carrier protein D1 , Ubiquitin-conjugating enzyme E2-17 kDa 1 , UBC4/5 homolog , Ubiquitin-conjugating enzyme E2 D1 , Ubiquitin-protein ligase D1 , SFT
Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
Reinheit:
95.00%
TMPJ-00999
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