FKBP25/FKBP3 Protein, Human, Recombinant (His)

Produktübersicht

• Artikelname: FKBP25/FKBP3 Protein, Human, Recombinant (His)
• Artikelnummer: TGM-TMPJ-01068
• Hersteller Artikelnummer: TMPJ-01068
• Alternativnummer: TGM-TMPJ-01068-1MG,TGM-TMPJ-01068-5UG,TGM-TMPJ-01068-10UG,TGM-TMPJ-01068-20UG,TGM-TMPJ-01068-50UG,TGM-TMPJ-01068-100UG,TGM-TMPJ-01068-200UG,TGM-TMPJ-01068-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: 25 kDa FKBP , FKBP-3 , Peptidyl-prolyl cis-trans isomerase FKBP3 , FKBP25 , FKBP-25 , Immunophilin FKBP25 , Rapamycin-selective 25 kDa immunophilin , PPIase FKBP3 , 25 kDa FK506-binding protein , FK506-binding protein 3 , Rotamase

Produktbeschreibung

FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.

Bilder

TMPJ-01068