TEM8/ANTXR1 Protein, Human, Recombinant (Isoform 4, His)

Produktübersicht

• Artikelname: TEM8/ANTXR1 Protein, Human, Recombinant (Isoform 4, His)
• Artikelnummer: TGM-TMPJ-01333
• Hersteller Artikelnummer: TMPJ-01333
• Alternativnummer: TGM-TMPJ-01333-1MG,TGM-TMPJ-01333-5UG,TGM-TMPJ-01333-10UG,TGM-TMPJ-01333-20UG,TGM-TMPJ-01333-50UG,TGM-TMPJ-01333-100UG,TGM-TMPJ-01333-200UG,TGM-TMPJ-01333-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: ATR , ANTXR1 , TEM8 , Tumor Endothelial Marker 8 , Anthrax Toxin Receptor 1

Produktbeschreibung

Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI).

Bilder

TMPJ-01333