Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1 , LAMTOR3 , Mp1 , Ragulator Complex Protein LAMTOR3 , Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3 , MEK-Binding Partner 1 , Mitogen-Activated Protein Kinase Scaffold Protein 1 , M
Mitogen-Activated Protein Kinase Scaffold Protein 1 (MAPKSP1) was identified as an interacting protein that belongs to the LAMTOR3 family. MAPKSP1 restricted to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. MAPKSP1 interacts with MAP2K1/MEK1 and MAPK2 and enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.
Molekulargewicht:
15 KDa (reducing condition)
TMPJ-01378
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