NKp30, along with NKp44 and NKp46, constitute a group of receptors termed Natural Cytotoxicity Receptors. These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells.
TMPK-00091
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