EPHB2 Protein, Cynomolgus, Recombinant (His)

Produktübersicht

• Artikelname: EPHB2 Protein, Cynomolgus, Recombinant (His)
• Artikelnummer: TGM-TMPK-00563
• Hersteller Artikelnummer: TMPK-00563
• Alternativnummer: TGM-TMPK-00563-5UG,TGM-TMPK-00563-10UG,TGM-TMPK-00563-20UG,TGM-TMPK-00563-50UG,TGM-TMPK-00563-100UG,TGM-TMPK-00563-200UG,TGM-TMPK-00563-500UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: DRT , Nuk , Sek3 , TYRO5 , EPHT3 , HEK5 , EphB2 , Qek2 , PCBC , EPHT3MGC87492 , EK5 , Cek5 , ERK , CAPB

Produktbeschreibung

EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2alpha is required for EPHB2 stabilization by hypoxia.

Bilder

TMPK-00563