LRRN1 Protein, Mouse, Recombinant (His)

Artikelnummer: TGM-TMPK-01030
Artikelname: LRRN1 Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPK-01030
Hersteller Artikelnummer: TMPK-01030
Alternativnummer: TGM-TMPK-01030-5UG,TGM-TMPK-01030-10UG,TGM-TMPK-01030-20UG,TGM-TMPK-01030-50UG,TGM-TMPK-01030-100UG,TGM-TMPK-01030-200UG,TGM-TMPK-01030-500UG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: Neuronal leucine-rich repeat protein 1 , LRN , NLRR1 , NLRR-1 , FIGLER3 , Leucine-rich repeat neuronal protein 1 , KIAA1497
Lrrn1 is required for the formation of MHB--loss of function leads to a loss of the morphological constriction and loss of Fgf8. Cells overexpressing Lrrn1 violate the boundary and result in a loss of cell restriction between midbrain and hindbrain compartments. Lrrn1 also regulates the glycosyltransferase Lunatic Fringe, a modulator of Notch signalling, maintaining its expression in midbrain cells which is instrumental in MHB boundary formation.
Molekulargewicht: 69.28 kDa (predicted). Due to glycosylation, the protein migrates to 80-90 kDa based on Tris-Bis PAGE result.
TMPK-01030