FANCA Protein, Human, Recombinant (His)

Produktübersicht

• Artikelname: FANCA Protein, Human, Recombinant (His)
• Artikelnummer: TGM-TMPY-02544
• Hersteller Artikelnummer: TMPY-02544
• Alternativnummer: TGM-TMPY-02544-5UG,TGM-TMPY-02544-10UG,TGM-TMPY-02544-20UG,TGM-TMPY-02544-50UG,TGM-TMPY-02544-100UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: FA-H , FA1 , FAA , FAH , FANCH , FACA , Fanconi anemia, complementation group A , FA

Produktbeschreibung

FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by hypersensitivity to DNA-damaging agents and oxidative stress. FANCA associates with the IkappaB kinase (IKK) signalsome via interaction with IKK2. Components of the FANCA complex undergo rapid, stimulus-dependent changes in phosphorylation, which are blocked by kinase-inactive IKK2.

Bilder

TMPY-02544