B3GNT2 Protein, Human, Recombinant (hFc)

Produktübersicht

• Artikelname: B3GNT2 Protein, Human, Recombinant (hFc)
• Artikelnummer: TGM-TMPY-03051
• Hersteller Artikelnummer: TMPY-03051
• Alternativnummer: TGM-TMPY-03051-5UG,TGM-TMPY-03051-10UG,TGM-TMPY-03051-20UG,TGM-TMPY-03051-50UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: B3GNT-2 , B3GNT , UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 , UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 , beta3GNT , BGNT2 , BETA3GNT , BGnT-2 , B3GN-T2 , B3GNT1

Produktbeschreibung

B3GNT2 belongs to the beta-1,3-N-acetylglucosaminyltransferase family. It is a type II transmembrane protein that prefers the substrate of lacto-N-neotetraose. Alternative splicing produced 2 isoforms of the human protein. B3GNT2 catalyzes the initiation and elongation of poly-N- acetyllactosamine chains. Enzymatic activities of some glycosyltransferases are markedly increased via complex formation with other transferases or cofactor proteins. B3GNT2 and beta3Gn-T8 can form a heterodimer in vitro and that the complex exhibits much higher enzymatic activity than either enzyme alone. It is found that up-regulation of beta3Gn-T8 in differentiated HL-60 cells may increase poly-N-acetyllactosamine chains by activating intrinsic B3GNT2.

Bilder

TMPY-03051