GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His)

Produktübersicht

• Artikelname: GGH/Glutamyl hydrolase gamma Protein, Human, Recombinant (His)
• Artikelnummer: TGM-TMPY-05055
• Hersteller Artikelnummer: TMPY-05055
• Alternativnummer: TGM-TMPY-05055-5UG,TGM-TMPY-05055-10UG,TGM-TMPY-05055-20UG,TGM-TMPY-05055-50UG,TGM-TMPY-05055-100UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: GGH/Glutamyl hydrolase gamma , gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) , gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) , GH

Produktbeschreibung

gamma-Glutamyl hydrolase (GGH) regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expressed enzyme that regulates intracellular folate metabolism for cell proliferation, DNA synthesis, and repair. cytoplasmic GGH might play a relevant role in the development and progression of invasive breast cancer.

Bilder

TMPY-05055