7-Hydroxyaristolochic acid A is a natural derivative of aristolochic acid. Aristolochic acid is nephrotoxic and carcinogenic, inhibits APE1/Nrf2/HO-1 axis-induced oxidative stress and apoptosis leading to nephrotoxicity, and induces apoptosis in NRK-52E cells via COX-2 and PGE2.
Molekulargewicht:
357.27
Reinheit:
99.47%
CAS Nummer:
[79185-75-4]
Formel:
C17H11NO8
Target-Kategorie:
DNA/RNA Synthesis
TN1004
TN1004
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