Rhetsinine is an aldose reductase inhibitor identified in Evodia rutaecarpa, with an IC50 value of 24.1 µM. At a concentration of 100 µM, Rhetsinine significantly reduces sorbitol accumulation, achieving an inhibition rate of 79.3%. This compound is applicable in research concerning diabetic complications, such as diabetic neuropathy and retinopathy.
Molekulargewicht:
319.357
CAS Nummer:
[526-43-2]
Formel:
C19H17N3O2
Target-Kategorie:
Reductase
TN10048
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