Cerberin is a cardiac glycoside found in C. odollam with cytotoxic and cardiac regulatory properties. It exhibits cytotoxicity against KB and NCI H187 cancer cells (IC50s = 1.92 and 1.24 µg/mL). Cerberin inhibits Na+/K+-ATPase, elevating intracellular sodium levels and prolonging action potential duration in cardiac cells.
Molekulargewicht:
576.72
CAS Nummer:
[25633-33-4]
Formel:
C32H48O9
Target-Kategorie:
ATPase
TN11117
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