Candidusin A, CAS [[81474-59-1]] Preis auf Anfrage
Artikelnummer:
TGM-TN11578
Hersteller Artikelnummer:
TN11578
Alternativnummer:
TGM-TN11578-10MG, TGM-TN11578-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Alternative Synonym:
CHNQD-0803
Candidusin A (CHNQD-0803) (Compound 4) is an AMPK activator with a KD of 47.28 nM. This compound can be isolated from the marine fungus Aspergillus candidus. Candidusin A exhibits cytotoxic activity against human prostate cancer cells (22Rv1, PC-3, and LNCaP cells) and induces apoptosis. It reduces lipogenic gene expression and fat deposition, downregulates the NF-kappaB-TNFalpha inflammatory axis to suppress inflammation, and improves liver injury and fibrosis. Candidusin A is applicable in the study of non-alcoholic steatohepatitis (NASH).
Molekulargewicht:
352.34
CAS Nummer:
[81474-59-1]
Formel:
C20H16O6
Target-Kategorie:
NF-kappaB|||Apoptosis|||TNF|||AMPK
TN11578
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