7-Oxo-beta-sitosterol (7-Ketositosterol), a phytosterol isolated from the fruit of x giganteus, has anticancer and antitumor activity, inhibits the proliferation of HL-60 acute myeloid leukemia (AML) cells, and stimulates the growth of HL-60 acute myeloid leukemia (AML) cells through the downregulation of the levels of S1P, p-44/42 ERK1/2 and p-NF-kappaB p65 proteins. -kappaB p65 protein levels to stimulate ceramide accumulation and apoptosis, and can be used to study breast cancer.
Molekulargewicht:
428.69
CAS Nummer:
[2034-74-4]
Formel:
C29H48O2
Target-Kategorie:
Apoptosis
TN3248
TN3248
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