(S)-(-)-Canadine (tetrahydroberberine) is a naturally occurring isoquinoline alkaloid, acting as a D2 receptor antagonist and 5-HT1A receptor agonist, capable of blocking dopamine-stimulated adenylate cyclase activity. (S)-(-)-Canadine also enhances gastrointestinal motility, blocks K(ATP) channels in substantia nigra pars compacta (SNc) dopaminergic neurons, and exerts neuroprotective effects.
Molekulargewicht:
339.39
CAS Nummer:
[5096-57-1]
Formel:
C20H21NO4
Target-Kategorie:
5-HT Receptor|||ATPase|||Dopamine Receptor
TN3574
TN3574
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