Ammocidin is an apoptosis inducer in Ras-dependent cells. It triggers apoptosis in Ras-dependent Ba/F3-V12 cells with an IC50 of 66 ng/mL. Additionally, Ammocidin significantly reduces the phosphorylation levels of MAPK and S6K, which mediate the anti-apoptotic functions of Ras.
Molekulargewicht:
1157.38
CAS Nummer:
[376590-20-4]
Formel:
C59H96O22
Target-Kategorie:
Apoptosis
TN9146
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