Jagged-1 (188-204) TFA(219127-21-6 free base) is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-alphaB activation.
Molekulargewicht:
2221.37
Reinheit:
99.48%
Formel:
C95H128F3N25O28S3
Target-Kategorie:
Gamma-secretase
TP1293
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