NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro.
Molekulargewicht:
1185.35
Reinheit:
96.92%
Formel:
C52H92N14O17
Target-Kategorie:
NADPH-oxidase
TP1886L1
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