FSLLRY-NH2 TFA is a is a protease-activated receptor 2 (PAR2) inhibitor. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.
Molekulargewicht:
910.99
Reinheit:
99.32%
Formel:
C41H61F3N10O10
Target-Kategorie:
Protease-activated Receptor
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