CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM. CALP2 acetate potently inhibits of adhesion and degranulation. CALP2 acetate is also a strong activator of alveolar macrophages. CALP2 acetate inhibits CaM-dependent phosphodiesterase activity and increases intracellular Ca2+ concentrations.
Molekulargewicht:
1357.7
Reinheit:
97.43%
Formel:
C68H104N14O13S
Target-Kategorie:
PDE|||CaMK
TP1909L1
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