CALP1 acetate is a calmodulin (CaM) agonist (Kd of 88 µM) that binds to the CaM EF-hand/Ca2+-binding site. CALP1 blocks calcium influx and apoptosis (IC50 of 44.78 µM) by inhibiting the open of calcium channel. CALP1 blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 activates CaM-dependent phosphodiesterase activity.
Molekulargewicht:
902.13
Reinheit:
99.63%
Formel:
C42H79N9O12
Target-Kategorie:
Calcium Channel|||CaMK
TP1910L1
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