Cell-permeable, myristoylated form of pep2m. Peptide inhibitor of the interaction between the C-terminus of the GluA2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF), a protein that regulates AMPA receptor function. Reduces postsynaptic currents in CA1 neurons, AMPA-mediated currents in cultured hippocampal neurons and AMPA receptor surface expression.
Molekulargewicht:
1383.8
CAS Nummer:
[1423381-07-0]
Formel:
C63H118N18O14S
Target-Kategorie:
PKC
TP1945
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