ARF(26-44), cell-permeable is an anti-tumor peptide derived from a specific amino acid sequence of the p14ARF tumor suppressor protein. It serves as an inhibitor of FoxM1, a forkhead box M1 transcription factor, and has demonstrated significant anti-tumor activity in the treatment of mouse hepatocellular carcinoma (HCC). This activity includes increasing apoptosis and reducing tumor cell proliferation and angiogenesis. ARF(26-44), cell-permeable is useful for research in cancer therapy.
Molekulargewicht:
3585.22
CAS Nummer:
[935732-44-8]
Formel:
C149H267N69O33S
Target-Kategorie:
Apoptosis
TP2731
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