123B9 is a tumor-homing agent characterized as a potent and selective agonist for EphA2 with a dissociation constant (Kd) of 4.0 µM. It specifically targets the ligand-binding domain of the EphA2 tyrosine kinase receptor. Notably, 123B9 does not significantly inhibit the ligand-binding domains of closely related receptors EphA3 and EphA4.
Molekulargewicht:
1321.79
CAS Nummer:
[2225868-19-7]
Formel:
C58H82ClFN12O20
Target-Kategorie:
Ephrin Receptor
TP2771
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