Ub4ix, a DUB/26S proteasome inhibitor, safeguards K48-linked Ub chains against cleavage by deubiquitinating enzymes (DUBs) and inhibits the proteasomal degradation of Ub-tagged proteins. Additionally, it diminishes the viability of Hela cells and triggers apoptosis, exhibiting an IC 50 value of 1.6 µM.
Molekulargewicht:
1767.91
CAS Nummer:
[2396736-46-0]
Formel:
C84H106N18O23S
Target-Kategorie:
Proteasome|||DUB|||Apoptosis
TP2873
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