Tkip is a specific inhibitor of JAK2. It binds to the autophosphorylation site of JAK2, thereby inhibiting JAK2 autophosphorylation and the phosphorylation of the IFN-gamma receptor subunit IFNGR-1. Tkip can suppress the antiviral activity of IFN-gamma and the expression of MHC class I molecules. Tkip is applicable in studies related to the IFN-gamma signaling pathway.
Molekulargewicht:
1684.03
CAS Nummer:
[716361-65-8]
Formel:
C93H118N16O14
Target-Kategorie:
JAK|||MHC
TP2958
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten