KRL74 is a cyclic peptide inhibitor that interferes with the interaction between the p6 domain of the HIV Gag protein and the UEV domain of the human TSG101 protein (p6/UEV), with an IC50 of 5.44 µM and a Kd of 11.9 µM. It also inhibits the budding of HIV from host cells, exhibiting an IC50 of 2 µM in virus-like particle (VLP) budding assays.
Molekulargewicht:
981.53
CAS Nummer:
[2423969-43-9]
Formel:
C50H61ClN10O9
Target-Kategorie:
Others|||HIV Protease
TP2983
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