CNI103 is a potent and metabolically stable inhibitor of the cell-permeable peptide, calcineurin. It selectively inhibits the interaction between calcineurin and NFATc3 (KD=16 nM), thereby preventing the activation of NFATc3 both in vitro and in vivo. CNI103 is applicable for research in acute respiratory distress syndrome (ARDS) and other inflammatory diseases.
Molekulargewicht:
2565.8
CAS Nummer:
[2366279-86-7]
Formel:
C116H180Cl2N36O26
Target-Kategorie:
Phosphatase
TP3040
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