CT-08 (CT8, Compound 3) is a macrolide Sec61 modulator that inhibits protein secretion in a signal sequence-dependent manner. It prevents the Sec61-mediated translocation of VCAMss-GLuc to the ER, resulting in the loss of luciferase activity. Additionally, CT-08 suppresses the expression of VCAM in transfected cells.
Molekulargewicht:
893.206
CAS Nummer:
[1000770-96-6]
Formel:
C50H80N6O8
Target-Kategorie:
Others
TP3082
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