Atrial natriuretic factor (1-28) (human, porcine) TFA exhibits antihypertensive activity by promoting sodium and urine excretion. It inhibits the release of adrenocorticotropic hormone (ACTH) and beta-endorphin by suppressing pro-opiomelanocortin (POMC) expression. Additionally, it elevates cGMP levels in RMIC cells, with an IC50 of 1.2 nM.
Molekulargewicht:
3080.46 (free base)
Formel:
C127H205N45O39S3.xC2HF3O2
Target-Kategorie:
Endogenous Metabolite
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