ETTAC-2 is an LRG1 PROTAC degrader that facilitates the ubiquitination and degradation of LRG1, with a DC50 of 8.38 µM. It inhibits the TGF-beta-Smad3 signaling pathway and reduces the secretion of proteins associated with fibrosis. ETTAC-2 can slow the progression of renal fibrosis.
Molekulargewicht:
1891.07
Formel:
C83H123N23O26S
Target-Kategorie:
TGF-beta/Smad|||PROTACs
TP3119
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
