WKYMVM-NH2 is a hexapeptide that activates neutrophils and myeloid cells through the FPRL1 and FPRL2 receptors, with EC50 values of 2 nM for HL-60-FPRL1 cells and 80 nM for HL-60-FPRL2 cells. It also induces chemotaxis in HL-60 cells stably expressing FPRL2, with optimal migration observed at concentrations ranging from 10 to 50 nM. Additionally, WKYMVM-NH2 stimulates neutrophils to produce superoxide with an EC50 of 75 nM. It is applicable in research focused on inflammatory diseases.
Molekulargewicht:
856.109
CAS Nummer:
[187986-11-4]
Formel:
C41H61N9O7S2
Target-Kategorie:
Others
TP3131
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