Ac-DMLD-CMK, CAS [[2588354-33-8]] Preis auf Anfrage

Artikelnummer: TGM-TP3236
Artikelname: Ac-DMLD-CMK, CAS [[2588354-33-8]] Preis auf Anfrage
Artikelnummer: TGM-TP3236
Hersteller Artikelnummer: TP3236
Alternativnummer: TGM-TP3236-10MG,TGM-TP3236-50MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Ac-DMLD-CMK is a peptide designed to target the caspase3-Gsdme signaling pathway in mice. It specifically inhibits the activation of caspase 3 and Gsdme, preventing the cleavage of Gsdme by caspase 3, which reduces pyroptosis. This process helps alleviate damage to renal tubular epithelial cells and decrease the secretion of inflammatory cytokines. Ac-DMLD-CMK can lower serum creatinine and blood urea nitrogen levels in mice induced by Cisplatin, thereby mitigating the progression of renal dysfunction. It holds potential for research into chemotherapy-induced nephrotoxicity.
Molekulargewicht: 567.053
CAS Nummer: [2588354-33-8]
Formel: C22H35ClN4O9S
Target-Kategorie: Caspase|||Pyroptosis
TP3236