GIP (22-51) human (Glucose-dependent Insulinotropic Peptide (22-51) human) is a potent pro-atherosclerotic peptide hormone composed of 30 amino acids. It activates the NF-kappaB signaling pathway, enhances the expression of MMP-8, and induces the expression of pro-inflammatory and pro-atherogenic proteins. Additionally, it increases intracellular free Ca2+ levels in THP-1 induced macrophages. GIP (22-51) human is useful for atherosclerosis research.
Molekulargewicht:
3181.56
CAS Nummer:
[957470-49-4]
Formel:
C140H226N44O41
Target-Kategorie:
MMP|||NF-kappaB|||Calcium Channel
TP3711
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