APY-d3 is an EphA4-LBD antagonist peptide with a Kd value of 138 nM. It is constrained in a biologically active beta-hairpin conformation through a disulfide bond linking its ends. APY-d3 is applicable for research in cancers such as gastric and pancreatic cancer, as well as in neurodegenerative diseases like amyotrophic lateral sclerosis and Alzheimers disease.
Target-Kategorie:
Ephrin Receptor
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