CCKBR agonist-1, CAS [[2923120-30-1]] Preis auf Anfrage
Artikelnummer:
TGM-TP4182
Hersteller Artikelnummer:
TP4182
Alternativnummer:
TGM-TP4182-10MG,TGM-TP4182-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
CCKBRagonist-1 (Compound 3r1) is a selective agonist for the cholecystokinin B receptor (CCKBR) that preferentially activates the Gq protein, with an EC50 of 35 pM. It significantly enhances neuronal survival at an EC50 of 37 pM. CCKBRagonist-1 improves cognitive decline in mice by upregulating alpha-secretase (ADAM10) and the calcium signaling molecule PLCB4, reduces the number of amyloid beta (Abeta) plaques, and promotes long-term potentiation (LTP). This compound is useful for Alzheimers disease research.
Molekulargewicht:
699.6
CAS Nummer:
[2923120-30-1]
Formel:
C32H39BrN6O7
Target-Kategorie:
Cholecystokinin Receptor|||Beta Amyloid|||MMP
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