Drp1 peptide inhibitor P110 (Compound P110) TFA is a selective Drp1 peptide inhibitor with neuroprotective properties. It suppresses the activation of Drp1, prevents Drp1 mitochondrial translocation induced by MPTP, and reduces MPTP-induced loss of dopaminergic neurons, damage to dopaminergic nerve terminals, and behavioral defects, making it useful for Alzheimers disease research. Furthermore, Drp1 peptide inhibitor P110 TFA mitigates mitochondrial and organ damage in animal models of Huntingtons disease, cerebral ischemic injury, and myocardial infarction.
Target-Kategorie:
Dynamin
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