GSK484 hydrochloride, CAS [[1652591-81-5]]

Produktübersicht

• Artikelname: GSK484 hydrochloride, CAS [[1652591-81-5]]
• Artikelnummer: TGM-TQ0067
• Hersteller Artikelnummer: TQ0067
• Alternativnummer: TGM-TQ0067-1MLX10MM(INDMSO),TGM-TQ0067-1MG,TGM-TQ0067-5MG,TGM-TQ0067-10MG,TGM-TQ0067-25MG,TGM-TQ0067-50MG,TGM-TQ0067-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: GTPL8577 , AOB6992

Produktbeschreibung

GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor. It binds to PAD4 with high affinity, with IC50 of 250 and 50 nM in the presence and absence of 2 mM calcium, respectively. GSK484 promotes the radiosensitivity of colorectal cancer (CRC) and inhibits NET formation in vitro and in vivo.

Produkteigenschaften

• Molekulargewicht: 510.03
• Reinheit: 98.32%
• CAS Nummer: [1652591-81-5]
• Formel: C27H32ClN5O3
• Target-Kategorie: PAD

Bilder

TQ0067