Alloc-Val-Ala-OH, CAS [[330970-70-2]] Preis auf Anfrage
Artikelnummer:
TGM-TYD-01870
Hersteller Artikelnummer:
TYD-01870
Alternativnummer:
TGM-TYD-01870-10MG,TGM-TYD-01870-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Alternative Synonym:
((Allyloxy)carbonyl)-L-valyl-L-alanine
Alloc-Val-Ala-OH (((Allyloxy)carbonyl)-L-valyl-L-alanine) serves as a building block in the synthesis of Tesirine, which is a clinical antibody-drug conjugate (ADC) featuring a pyrrolobenzodiazepine (PBD) dimer payload. The Val-Ala sequence is cleaved specifically by cathepsin B. The Alloc group is stable towards piperidine and TFA, yet can be easily removed under mild conditions via palladium-catalyzed allyl transfer.
Molekulargewicht:
272.298
CAS Nummer:
[330970-70-2]
Formel:
C12H20N2O5
TYD-01870
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