Fmoc-PEG2-Val-Cit-PAB-OH, CAS [[2055024-59-2]] Preis auf Anfrage

Artikelnummer: TGM-TYD-01945
Artikelname: Fmoc-PEG2-Val-Cit-PAB-OH, CAS [[2055024-59-2]] Preis auf Anfrage
Artikelnummer: TGM-TYD-01945
Hersteller Artikelnummer: TYD-01945
Alternativnummer: TGM-TYD-01945-10MG,TGM-TYD-01945-50MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Fmoc-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker that features a Boc-protected amine, hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzyl alcohol on the PAB can be used for conjugating reactive groups (e.g., PNP) to attach a payload. The Fmoc protecting group is removable with piperidine, revealing a primary amine for amide bond formation in conjugation reactions. The Val-Cit-PAB segment is cleaved by cellular proteases to efficiently release the payload inside cells.
Molekulargewicht: 760.876
CAS Nummer: [2055024-59-2]
Formel: C40H52N6O9
Target-Kategorie: ADC Linker
TYD-01945