Fmoc-PEG2-Val-Cit-PAB-OH, CAS [[2055024-59-2]] Preis auf Anfrage
Artikelnummer:
TGM-TYD-01945
Hersteller Artikelnummer:
TYD-01945
Alternativnummer:
TGM-TYD-01945-10MG,TGM-TYD-01945-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Fmoc-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker that features a Boc-protected amine, hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzyl alcohol on the PAB can be used for conjugating reactive groups (e.g., PNP) to attach a payload. The Fmoc protecting group is removable with piperidine, revealing a primary amine for amide bond formation in conjugation reactions. The Val-Cit-PAB segment is cleaved by cellular proteases to efficiently release the payload inside cells.
Molekulargewicht:
760.876
CAS Nummer:
[2055024-59-2]
Formel:
C40H52N6O9
Target-Kategorie:
ADC Linker
TYD-01945
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