Boc-PEG2-Val-Cit-PAB-OH, CAS [[2055024-55-8]] Preis auf Anfrage
Artikelnummer:
TGM-TYD-01991
Hersteller Artikelnummer:
TYD-01991
Alternativnummer:
TGM-TYD-01991-10MG,TGM-TYD-01991-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Boc-PEG2-Val-Cit-PAB-OH is an enzymatically cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzyl alcohol on PAB can be utilized for attachment to reactive groups (such as PNP) to connect with a drug payload. The Boc protecting group can be removed with acid, revealing a primary amine that serves for coupling reactions to form an amide. The Val-Cit-PAB segment is cleaved by cellular proteases, facilitating the effective release of the payload inside the cell.
Molekulargewicht:
638.753
CAS Nummer:
[2055024-55-8]
Formel:
C30H50N6O9
Target-Kategorie:
ADC Linker
TYD-01991
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