(R)-Phe-A110/B319 is a hapten and a selective binder for tumor-associated antigens. It exhibits a 20-fold higher affinity for the H1047R mutant of p110alpha within the p110alpha/p85alpha PI3K complex. This compound is applicable in studies on the activation of conditional chimeric antigen receptor T (CAR-T) cells and tumor targeting.
Formel:
C62H57F3N8O14S
Target-Kategorie:
Others
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