GST-S5a

Artikelnummer: UBP-A3301
Artikelname: GST-S5a
Artikelnummer: UBP-A3301
Hersteller Artikelnummer: A3301
Alternativnummer: UBP-A3301-100
Hersteller: UBPBio, LLC
Kategorie: Sonstiges
Spezies Reaktivität: Human
S5a is one of the integral Ub receptors of the 26S proteasome. Its N-terminal vWA domain interacts with Rpn9 and Rpn10 on the 26S proteasome. The C-terminal domain of S5a contains two Ub-interacting motifs (UIMs) that bind Ub and Ub chains. S5a prefers to bind polyUb chains, it also binds proteins containing a Ub-like domain. It may directly recognize ubiquitinated proteins or coordinate with other Ub receptors to target substrates for proteasomal degradation.
Molekulargewicht: 40.7 kDa
NCBI: 002810
Puffer: 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol
Quelle: E. coli recombinant