6xHis-UbE2W

Produktübersicht

• Artikelname: 6xHis-UbE2W
• Artikelnummer: UBP-C4001
• Hersteller Artikelnummer: C4001
• Alternativnummer: UBP-C4001-100
• Hersteller: UBPBio, LLC
• Kategorie: Sonstiges
• Spezies Reaktivität: Human

Produktbeschreibung

Ube2W is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It has been shown to catalyze monoubiquitination of Fanconi anemia complementation group L (FANCL), an E3 Ub ligase. The FANCL is part of a complex that is able to monoubiquitinate FANCD2 during DNA repair. Ube2W can also interact with the RING domain of the breast and ovarian cancer susceptibility protein called BRCA1.

Produkteigenschaften

• Molekulargewicht: 18.7 kDa
• NCBI: 001001481
• Puffer: 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol
• Quelle: E. coli recombinant