Nickel chelate resins recognize two exposed histidines for an appreciable retention of a protein with a 4X or 6XHis tag. Nickel XPure Agrose Resin provides the advantages of the Nickel cation with the high flow rates of the highly cross-linked agarose beads. Except for batch purification, this product is specially suitable for large scale His-tagged protein purification using FPLC.The XPure series of resins are made for large scale and fine purification using a high-performance liquid chromatography (HPLC) system.
